The operation and safety of transportation facilities is relevant to all users. In addition to passenger vehicles, users include pedestrians, bicyclists, freight, and transit. The purpose of this chapter is to provide guidance on multimodal analysis by providing flowcharts for analysis methodology selection, templates for requisite data collection, step-by-step guides on various analysis methods, and references to additional resources. The chapter’s intent is to provide a baseline for analysis and supplementary sources that could aid in a more detailed analysis.